Crescentic glomerulonephritis in a patient with neuromyelitis optica (Devic´s syndrom)

Dominik Bös, Michael Praktiknjo, Winfried Willinek, Joachim Velden, Rainer Woitas

Abstract


Neuromyelitis optica (NMO) or Devic´s syndrome is an inflammatory, demyelinating disease of the central nervous system leading to optical neuritis and myelitis. Etiology of NMO is unknown, although autoimmune disorders involving IgG autoantibodies specific for aquaporin 4 are suspected. These autoantibodies are associated with 73% sensitivity 93% specificity for NMO helping to distinguish NMO from other demyelinating disorders. Some cases of NMO are reported in association with systemic lupus erythematosus and Sjögren`s syndrome. Here we report a patient presenting with NMO and concomitantly occurring rapid progressive crescentic intra- and extracapillary crescentic glomerulonephritis.

Full Text:

PDF


DOI: https://doi.org/10.5430/crim.v2n1p86

Refbacks

  • There are currently no refbacks.


Case Reports in Internal Medicine

ISSN 2332-7243(Print)  ISSN 2332-7251(Online)

Copyright © Sciedu Press

To make sure that you can receive messages from us, please add the ‘sciedupress.com’ domains to your e-mail 'safe list'. If you do not receive e-mail in your 'inbox', please check your 'spam' or 'junk' folder.