Olmesartan - associated sprue-like enteropathy and colagenous colitis: A case report and review of literature

Abstract

Olmesartan, an angiotensin II receptor blocker, is widely used for the treatment of hypertension. An association of olmesartan use with a reversible, sprue-like enteropathy has recently been recognized. There are also rare reports of olmesartan use and the combination of sprue-like enteropathy and collagenous colitis. We report a case of an elderly female who presented with both severe collagenous sprue and collagenous colitis associated with the use of olmesartan, with complete clinical and histologic recovery after discontinuation of the drug.