Systemic amyloidosis as a cause of cerebral thrombo-embolic stroke: A case report

Abstract

Systemic amyloidosis is a rare clinical disorder and can lead to single organ or fatal multiple organ failure, heart and kidneys are the most affected organs. Currently, there are no relevant guidelines and recommendations about the treatment of systemic amyloidosis. Ischemic stroke is an uncommon complication of systemic amyloidosis and patients with systemic amyloidosis may carry a worse prognosis. We report a case of cerebral thrombo-embolism in a 40-year-old woman due to indicated systemic amyloidosis, she received intravenous rt-PA thrombolytic therapy in hyperacute phase of ischemic stroke and this case proved that intravenous rt-PA thrombolysis therapy may be an effective treatment for acute cerebral thrombo-embolic stroke patients with systemic amyloidosis.