Research progress of SALL4 gene in human malignant tumor

Abstract

At present, malignant tumor is a serious threat to human health. Its pathogenesis is complicated and caused by the interaction of various carcinogenic factors in human body. Human sal-like protein 4 (SALL4) is a newly discovered gene. It can play an important role in the function of embryonic stem cells since it is with protein transcription factor of C2H2 zinc fingers. Studies have found that mutations of the gene often lead to the occurrence of malignant tumors. This article reviews the molecular mechanism of SALL4 in the occurrence and development of malignant tumors and its role in the diagnosis and treatment of malignant tumors.