Effects of integrated traditional Chinese and western medicine on the vision recovery and serum trace elements of patients with herpes simplex keratitis

Abstract

Objective: To explore the effects of integrated traditional Chinese and western Medicine on the vision recovery and serum trace elements in patients with herpes simplex keratitis.

Methods: A total of 86 cases of HSK patients admitted in Baogang Hospital of Inner Mongolia from January 2015 to October 2016 were selected and divided randomly into the observation group (n = 43) and the control group (n = 43) according to the random number table. The control group was treated with ganciclovir eye drops and chondroitin sulfate eye drops, and the observation group was treated with Qinggan Mingmu Decoction on the basis of the control group. The 2 groups were treated for 4 weeks continuously. The clinical efficacy was compared between two groups. The vision recovery, serum trace elements and tear immune factor levels were also compared between two groups before and after treatment.

Results: After treatment, the effective rate of treatment in the observation group was significantly higher than that in the control group (p < .05); in the observation group of patients, visual analogue scale (VAS) score and visual acuity after treatment were obviously higher than those before treatment, and also remarkably higher than those in the control group of patients (p < .05); after treatment, the levels of Fe, Ca and Cu ions in the observation group were significantly lower than those in the control group and before treatment (p < .05); after treatment, the level of zinc ions in the serum in the observation group was significantly higher than that before treatment and in the control group (p < .05); after treatment, the levels of tear IgA, IgG and C3 in the observation group were prominently higher than those before treatment and in the control group (p < .05).

Conclusions: In the treatment of HSK, integrated traditional Chinese and western medicine can promote effectively the vision recovery, regulate the level of trace elements in the serum and enhance the level of tear immune factors, with the clinical efficacy better than the treatment of western medicine alone.