Effects of compound danshen dripping pills on the levels of serum inflammatory factors, brain natriuretic peptide and blood lipid in CABG postoperative patients

Abstract

Objective: To explore the effects of compound danshen dripping pills on the levels of serum inflammatory factors, brain natriuretic peptide (BNP) and blood lipid in CABG postoperative patients.

Methods: 156 cases of patients who were given CABG from January 2015 to January 2018 in Baogang Hospital were chosen and randomly divided into the observation group (n = 78) and the control group (n = 78). Both groups were given conventional drugs, simultaneously, the observation group was given compound danshen dripping pills. The treatment lasted 3 months. The clinical efficacy was compared between two groups of patients, and the levels of serum inflammatory factors, plasma BNP and blood lipid before and after treatment in two groups of patients were detected in order to make a comparison in the incidence of adverse cardiac events between two groups of patients.

Results: After treatment, the total effective rate of treatment in the observation group was significantly higher than that in the control group; in the two groups, the levels of serum interleukin-6 (IL-6), interleukin-8 (IL-8), C-reactive protein and plasma BNP after treatment were obviously lower than those before treatment, and these indicators in the observation group were lower than those in the control group (p < .05); the levels of TG, TC and LDL-C in two groups were obviously lower (p < .05) with the level of HDL-C significantly higher (all p < .05), and the descending or ascending range of each indicator in the observation group was obviously larger than that in the control group (p < .05); in the follow-up visit, the incidence of adverse cardiac events in the observation group of patients was significantly lower than that in the control group of patients (p < .05).

Conclusions: Compound danshen dripping pills can effectively reduce the levels of serum inflammatory factors and BNP, regulate blood lipid metabolism and reduce the incidence of adverse cardiac events in CABG postoperative patients.